Bay IVF - Advanced Reproductive Care                                Palo Alto  650-322-0500


Indications for Soft-IVF

The majority of eligible patients who need conventional In Vitro Fertilization will also be candidates for Soft-IVF. For most, the choice will depend on whether you prefer to minimize the number of treatment injections and lower the treatment cost or whether you wish to maximize the cumulative probability of a successful outcome from all available embryos.

Indications for Soft-IVF are similar to for conventional In Vitro Fertilization:

  • Long-standing infertility (no contraception use for a year and a half or more)
  • Male factor infertility
  • History of tubal blockage and pelvic adhesions
  • Infertility associated with endometriosis
  • Infertility associated with mild to moderate polycystic ovary syndrome (PCOS)
  • Unexplained infertility
  • An alternative to intrauterine inseminations (IUI) and ovarian stimulation treatment

Not all patients are good candidates for Soft-IVF. For some, the conventional In Vitro Fertilization or Donor Egg In Vitro Fertilization will be the most appropriate treatment option. It is our goal to help you select a treatment which will most likely, most expeditiously, and most economically result in a successful outcome.

The following list outlines treatment requirements related specifically to Soft-IVF:

  1. Compared with conventional In Vitro Fertilization, Soft-IVF commonly results in fewer eggs developing within the ovaries. It is important that the egg quality be sufficiently high. You must be must be 40 years or younger to be a candidate for the Soft-IVF treatment.

  2. You must have both ovaries, and there must be no ovarian cysts larger than 12 mm.

  3. Your menstrual cycle length must be between 21 and 35 days. Most women with irregular menstrual periods do not respond well to ovarian stimulation with the oral medications used in the Soft-IVF treatment.

  4. You must have a normal number (10-24) of antral follicles (small dark circles within each ovary) on your initial ultrasound at Bay IVF. If your antral follicle count is outside of this range, your ovaries will likely not respond well to ovarian stimulation with the oral medication used in the Soft-IVF treatment, and conventional IVF will be a better option for you.

  5. Your FSH (follicle stimulating hormone) and estrogen levels must indicate that your ovaries can respond to stimulation with oral medications: FSH must be 9.0 or less and estrogen level must be 50 or less.

  6. Male partner’s semen must have a sufficient number of normal quality sperm. If sperm normal morphology is less than 5% or sperm total motility is less than 5%, conventional IVF, which typically results in a higher number of eggs available for fertilization, will be a better option for you.

The IVF or Soft-IVF page provides additional information about the differences between conventional In Vitro Fertilization and Soft-IVF.

Please use the following links for additional information about Soft-IVF and to request a consultation.


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